The Best U101 freezers

The Best U101 Freezers for Your Smart Kitchen.

Temperature loss occurs whenever you open a freezer door, meaning your unit has to work extra to attain the set temperature.


The U101 Freezer is an Ultra-Low Temperature Freezer. They are custodians of temperature-sensitive biological samples. ULT freezers are deployed in biobanking and pharmaceutical laboratories to store proteins, DNA, antibodies, small molecules, enzymes, and more.

It is important to note that while laboratory freezers offer temperature control of -10°C to -25°C, ultra-low freezers operate within the -60°C– -86°C range. These appliances have monitoring capabilities that allow lab managers to analyze and monitor sample safety and inventory remotely. ULT freezers have a service life of about 12 to 15 years, depending on the manufacturer.

There are various models of ULT units, some are unique, and some are personal-size upright freezers that are compact enough to fit on your lab bench or underneath it. You can also opt to stack them on top of another unit; some are spacious and attain cold enough temperatures to handle various laboratory freezing requirements adequately. U101 Freezers are the standard when it comes to maximizing the storage capacity of samples. Using ultra-efficient, ultra-compact vacuum insulation panels in combination with traditional insulation, this slims freezer wall thickness from 130 mm to 80 mm. These models are ideal for labs short on space. The upright models of U101 have a limited footprint, specially designed for small labs. They can be made to fit under a standard bench or be stacked.


What are Ultra-Low Temperature Freezers?

Ultra-low temperature freezers (ULT) are freezers that maintain a temperature range from -45°C (-49°F) to -86°C (-122°F). ULT units are primarily found in hospitals, biomedical engineering facilities, and blood blanks. What can you keep in the U101 freezer? In this appliance, you can store biological samples of blood, semen, bacteria, viruses, tissues, and cell samples. Ultra-low temperature freezers come in different shapes and sizes to meet a wide range of lab needs. Small countertop models include benchtop, under-counter or chest freezers, and high-quality upright freezers. 

Because variation is so broad, you will have to consider every consideration for one. You will expect nothing but the best and want your freezer to offer uninterrupted service while enduring the test of time. It is essential to make the right choice when buying an ultra-low temperature freezer.

How good is the U101 freezer?

For some units, this freezer is equipped with reliable heavy-duty compressors (a 2-stage cascade cooling system). You can reuse the appliance quickly after cleaning or defrosting due to its quick pull-down time. Whenever you open the door of a freezer, temperature loss occurs, meaning your machine has to work extra to attain the set temperature not so with the U101, which has short recovery times after opening and built-in voltage stabilizers to provide extra sample safety.


The U101 Upright Freezers can be equipped with CO2/LN2 backup systems and a chart recorder. This significantly augments reliability. It is also possible to monitor the freezers remotely by using the TCA-3 temperature monitor system.


The U101 Freezer has models that are fitted with a total capacity of 3.6 cubic feet and an ultimate low temperature of -86°C; this makes the U101 spacious and cold enough for a range of laboratory freezing applications. This unit comes with an onboard digital display that allows the user to input various information, including temperature set point, low alarm, high alarm, lock, current temperature, and more. The U101 has great user controls with simple and easy-to-read buttons. The U101 Freezer can attain low temperatures while consuming a reduced amount of power.

The U101 features vacuum insulation panels, inner doors with gaskets for minimal cold air loss; an easy-to-read LED panel, an intelligent diagnostic system, easy internal door removal, entire stainless steel interior, password protection of alarms and setpoints, reduced noise levels, and a temperature range of -50° to -86°C.

Global ULT freezers market report 2021

The figure above shows Global ULT Freezers Market Report 2021 which is experiencing robust growth. 


U101 freezer reviews:

A reviewer assessed the U101 freezer as being of good quality. He noted that the product’s dimensions are unique and attractive as they could be put under the lab desk to optimize the available space in the room. It is not too noisy. The U101 Freezer is fitted with a button on the side to allow an airflow arrival when users want to open the door without damaging the rubber seal.


A second reviewer called the U101 value for money. He termed the equipment as very robust. When the reviewer first purchased it, the freezer was kept at room temperature for more than a year, and after that, it was moved to an air-conditioned room. It survived and is still working after almost eight years.


Another reviewer was impressed by its compactness even though it was a little freezer. Its temperature monitoring feature played a vital role during power failures, and it was perfect for use in a lab as the noise levels were okay.


How reliable is the U101 freezer? 

The Blizzard™ HC VIP NU-99338J

  • Overview: This unit from Blizzard trumpets reliable performance and focuses on storing cancer cells, cord blood, T-cells, stem cells, and organ/tissue samples. It is fitted with an eco-friendly hydrocarbon with low emissions while maintaining optimal performance and maximum storage.
  • Orientation: Upright Freezer
  • 2-inch Box Capacity: 96
  • Exterior Dimensions: 32.0” W x 35.2” D x 72.7” H  
  • Interior Dimensions: 18.3” W x 24.8” D x 45.9” H
  • Temperature Range: 10-32°C
  • Volume Capacity: 11.9 cubic ft. (388-Liter)
  • Defrost Type: Manual

Blizzard HC VIP NU-99420J

  • Overview: It is an environmentally friendly ultra-low temperature freezer with hydrocarbon refrigerants that are non-toxic and non-ozone depleting. This unit is energy efficient therefore minimizing your total cost of ownership overall. It is designed for maximum storage; the freezer is ergonomic and includes a self-checking diagnostic system.
  • Orientation: Chest freezer and accessed from the top.
  • 2-inch Box Capacity: 27
  • Temperature Range: -86°C
  • Volume Capacity: 14.8 cubic ft. (420-Liter)


The Eppendorf CryoCube® F740

  • Overview: This is a high-quality, full stainless steel freezer with higher capacity. It is designed to store more samples with class-leading security. It is designed ergonomically and supports optimal workflow and energy use. This unit is fitted with a touchscreen display.
  • Orientation: Upright freezer with left/right handles.
  • Maximum Power Consumption: 10,500 W
  • Exterior Dimensions: Not listed.
  • Temperature Range: -50°C to -86°C
  • Volume Capacity:  740 L (26.1 cubic ft.)
  • How much is this U101 freezer worth? Average Cost: $21,000


Innova® U101

  • Overview: The Innova ULT freezer is fitted with classic insulation foam and vacuum insulation. This makes it possible to provide durable and long-lasting ULT technology. These units are well suited for a smaller lab or facility and easily fit below a bench. They can also be stackable. The interior is stainless steel for easy maintenance and has a powder-coated exterior.
  • Orientation: Upright freezer with left/right handles.
  • Maximum Power Consumption: 7,400 W
  • Exterior Dimensions: 90 W x 56.6 D cm  
  • Temperature Range: -50°C to -86°C
  • Volume Capacity: 101 L (3.6 cubic ft.)
  • Average Cost: $12,000

CryoCube® FC660

  • Overview: This ULT freezer is a chest freezer, which means it is accessed from the top. For this reason, the manufacturer claims to store samples safer than a conventional upright freezer. This freezer is popular because it is rated as energy-efficient, the unit also delivers long-term sample preservation, and it is considered hassle-free. The CryoCube comes with a 2-stage cascade cooling system, which makes it reliable during all cooling processes.
  • Orientation: Chest freezer and accessed from the top.
  • Maximum Power Consumption: 10,600 W
  • Exterior Dimensions: 207 W x 84 D cm
  • Temperature Range: -50°C to -86°C
  • Volume Capacity: 660 L (23.3 cubic ft.)
  • Average Cost: $18,000

Low-Temperature Solid Door Laboratory/Pharmacy Freezers

  • Overview: Manufactured by Continental Scientific, these freezers are a more modern choice, equipped with self-closing doors and automatic interior lighting. The units have an external digital thermometer, and their steel shelves are coated with epoxy for ultimate protection. You can choose between three models: 1 section reach-in, 2 section reach-in, and 3 section reach-in.
  • Orientation: Upright freezers with left/right handles.
  • Defrost Type: Automatic electric.
  • Exterior Dimensions: 
    • 1 section reach-in: 85.5” H x 42” D x 31 ⅝” W
    • 2 section reach-in: 85.5” H x 42” D x 64” W
    • 3 section reach-in: 85.5” H x 42” D x 90” W
  • Temperature Range: -30°C to -18°C
  • Volume Capacity:
    • 1 section reach-in: 65 cubic ft. 
    • 2 section reach-in: 133 cubic ft.
    • 3 section reach-in: 187 cubic ft.


Low-Temperature Glass Door Laboratory/Pharmacy Freezers

  • Overview: Also manufactured by Continental Scientific, they are similar to the Solid Door Freezers, but these units feature see-through glass doors instead. These freezers also come in three models: 1 section reach-in, 2 section reach-in, and 3 section reach-in. Enjoying a design similar to their solid-door sibling, complete with the modern style, the Low-Temperature Glass Door freezers are fitted with a thermal expansion valve that manages the refrigerant flow to allow quick recovery.
  • Orientation: Upright freezers with left/right handles.
  • Defrost Type: Automatic electric.
  • Exterior Dimensions: 
    • 1 section reach-in: 85.5” H x 42” D x 31 ⅝“ W
    • 2 section reach-in: 85.5” H x 42” D x 64” W
    • 3 section reach-in: 85.5” H x 42” D x 90” W
  • Temperature Range: -24°C to -18°C
  • Volume Capacity:
    • 1 section reach-in: 65 cubic ft. 
    • 2 section reach-in: 133 cubic ft.
    • 3 section reach-in: 187 cubic ft.

Frequently Asked Questions:

Q: How does an ultra-low temperature freezer work?

An ultra-low freezer is usually one of two design options; it is either a single high-power compressor hermetically sealed or two cascade compressors. The two cascade model is two refrigeration circuits connected so that the evaporator of one cools the condenser of the other, making possible the condensation of the compressed gas in the first circuit.

There are also air-cooled condensers which are used in laboratory ultra-low freezer systems. They consist of tubular batteries (copper or copper-aluminum) arranged to provide as much surface heat transfer as possible. An energy driven fan forces the circulation of the cooling air and the expansion of the refrigerant fluids is obtained by capillary tubes.

In this configuration, evaporation occurs through steel plate heat exchangers fitted inside the chamber or by a coil. The coil in the cabinet eliminates the efficiency issue in the heat exchange of freezers with the ring in the insulation cavity.


Q: Where is the ultra-low freezer used?

Low-temperature freezers are used for a wide range of applications, such as for biological and biotech storage in research universities, medical centers, hospitals, blood banks, and forensic labs.

An ultra-low freezer is ideal for storing biological samples like DNA/RNA, plant and insect samples, autopsy materials, blood, plasma and tissues, chemicals, drugs, and antibiotics.

Manufacturing firms and performance testing labs also use ultra-low temperature freezers to regulate the ability of products and machinery to perform reliably under severe low-temperature conditions, such as those found in the Arctic regions.


As expressed, there are a lot of factors to consider when it comes to finding the right ultra-low temperature freezer for your use. You are advised to think about the energy consumption, location for the storage, and what you intend to store in the freezer. All of these considerations will go into the ultimate choice of which ULT freezer you eventually choose to buy.





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